­
­
­
­

Inventi Impact: Urology & Nephrology

Articles

  • Inventi:hun/28067/19
    Efficacy of Standard and Low Dose Hydrochlorothiazide in the Recurrence Prevention of Calcium Nephrolithiasis (NOSTONE Trial): Protocol for a Randomized Double-Blind Placebo-Controlled Trial
    Research 2019 : April - June
    Nasser A Dhayat, Nicolas Faller, Olivier Bonny, Nilufar Mohebbi, Alexander Ritter, Lisa Pellegrini, Giulia Bedino, Carlo Schonholzer, Reto M Venzin, Carina Husler, Irene Koneth, Rosaria Del Giorno, Luca Gabutti, Patrizia Amico, Michael Mayr, Urs Odermatt, Florian Buchkremer, Thomas Ernandez, Catherine Stoermann-Chopard, Daniel Teta, Felix Rintelen, Marie Roumet, Irina Irincheeva, Sven Trelle, Luca Tamo, Beat Roth, Bruno Vogt, Daniel G Fuster

    Background: Nephrolithiasis is a global healthcare problem with a current lifetime risk of 18.8% in men and 9.4% in\nwomen. Given the high cost of medical treatments and surgical interventions as well as the morbidity related to\nsymptomatic stone disease, medical prophylaxis for stone recurrence is an attractive approach. Thiazide diuretics have\nbeen the cornerstone of pharmacologic metaphylaxis for more than 40 years. However, evidence for benefits and\nharms of thiazides in the prevention of calcium containing kidney stones in general remains unclear. In addition, the\nefficacy of the currently employed low dose thiazide regimens to prevent stone recurrence is not known..............

    How to Cite this Article
    CC Compliant Citation: Dhayat, Nasser A., et al. \"Efficacy of standard and low dose hydrochlorothiazide in the recurrence prevention\nof calcium nephrolithiasis (NOSTONE trial): protocol for a randomized double-blind placebo-controlled trial.\" BMC nephrology 19.1\n(2018): 349, https://doi.org/10.1186/s12882-018-1144-6, http://creativecommons.org/licenses/by/4.0/.
    Download Full Text